Endocrine Abstracts

Cranial Diabetes Insipidus is a rare diagnosis and rarer still postpartum. We present the case of 24-year-old woman who developed CDI following pregnancy. The patient had developed polydipsia and polyuria 5 months following pregnancy. The pregnancy had been complicated by Gestational Diabetes Mellitus and a large Postpartum Haemorrhage. The patient reported feeling fatigued, lightheaded and she stated a need to drink water frequently: ~ 8 litres throughout the day and 4 litres...

We present the case of a 77-year-old woman with a medical history of diabetes mellitus type 2 and hypothyroidism who was admitted to hospital after having had episodes of recurrent symptomatic hypoglycaemia. The patient had diabetes mellitus type 2 for 26 years and this had gone into remission over the previous 2 years: she had been having recurrent hypoglycaemia necessitating reduction in insulin doses and then subsequent discontinuation of therapy altogether. There was a his...

We are reporting a 33 years old female, known case of primary adrenal failure who presented to our emergency department feeling generally unwell, lethargic and short of breath, She found to be hypothermic, hypotensive and hypoglycaemic. ECG showed low voltage QRS complex with prolonged QT intervals and ECHO confirmed moderate to severe left ventricular dysfunction with features of ’broken heart’ and ballooning suggestive of Takusobo cardiomyopathy. In our case report...

The prolactin receptor (PRLR) is a member of the class I cytokine receptor family that signals predominantly through the JAK2–STAT5 pathway. To date, PRLR mutations have not been established to be associated with any disorders. Here, we report a PRLR mutation (His188Arg) that caused familial hyperprolactinaemia in three sisters, two of whom presented with oligomenorrhea and one with infertility. The hyperprolactinaemia was not associated with pituitary tumours, which were...